We offer:
- Tailored and comprehensive drug discovery services for antimicrobials designed to accelerate our partners’ programs.
- A distinctive drug discovery approach grounded not only extensive experience but in deep insight, originality, and innovative thinking.
- Over half a century of proven expertise and a strong track record in antimicrobial drug discovery
- Extensive experience spanning AMR, emerging viruses, and malaria/NTDs, as well as viral gastroenteritis drug discovery.
- Robust evaluation systems, including clinical isolate testing, AMR challenge panels, and a variety of animal infection models.
Our multidisciplinary team manages projects seamlessly from target identification through to IND:
- Chemistry: HtL (Hit to Lead) and LO (Lead Optimization) SAR studies.
- Microbiology: Comprehensive in vitro/in vivo assays along with preclinical studies
- Safety: in vitro/in vivo assays, supported by through preclinical studies
- DMPK: in vitro ADME screening, in vivo pharmacokinetic studies, and preclinical studies
- CMC: Process chemistry, formulation development, analytical testing, GMP manufacturing consultation.